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Research Article

Critical Role of Perforin-dependent CD8+ T Cell Immunity for Rapid Protective Vaccination in a Murine Model for Human Smallpox

  • Melanie Kremer equal contributor,

    equal contributor Contributed equally to this work with: Melanie Kremer, Yasemin Suezer, Asisa Volz

    Affiliation: Institute for Infectious Diseases and Zoonoses, University of Munich LMU, Muenchen, Germany

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  • Yasemin Suezer equal contributor,

    equal contributor Contributed equally to this work with: Melanie Kremer, Yasemin Suezer, Asisa Volz

    Affiliation: Paul-Ehrlich-Institut, Langen, Germany

    X
  • Asisa Volz equal contributor,

    equal contributor Contributed equally to this work with: Melanie Kremer, Yasemin Suezer, Asisa Volz

    Affiliation: Institute for Infectious Diseases and Zoonoses, University of Munich LMU, Muenchen, Germany

    X
  • Theresa Frenz,

    Affiliation: Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research, Braunschweig, and Hannover Medical School, Hannover, Germany

    X
  • Monir Majzoub,

    Affiliation: Institute of Veterinary Pathology, University of Munich LMU, Muenchen, Germany

    X
  • Kay-Martin Hanschmann,

    Affiliation: Paul-Ehrlich-Institut, Langen, Germany

    X
  • Michael H. Lehmann,

    Affiliation: Institute for Infectious Diseases and Zoonoses, University of Munich LMU, Muenchen, Germany

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  • Ulrich Kalinke,

    Affiliation: Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research, Braunschweig, and Hannover Medical School, Hannover, Germany

    X
  • Gerd Sutter mail

    gerd.sutter@lmu.de

    Affiliation: Institute for Infectious Diseases and Zoonoses, University of Munich LMU, Muenchen, Germany

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  • Published: March 01, 2012
  • DOI: 10.1371/journal.ppat.1002557

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