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Research Article

β-Microseminoprotein Endows Post Coital Seminal Plasma with Potent Candidacidal Activity by a Calcium- and pH-Dependent Mechanism

  • Anneli M. L. Edström Hägerwall,

    Affiliation: Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden

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  • Victoria Rydengård,

    Affiliation: Division of Dermatology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden

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  • Per Fernlund,

    Affiliation: Division of Clinical Chemistry, Department of Laboratory Medicine Malmö, Lund University, Malmö, Sweden

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  • Matthias Mörgelin,

    Affiliation: Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden

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  • Maria Baumgarten,

    Affiliation: Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden

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  • Alexander M. Cole,

    Affiliation: Burnett School of Biomedical Sciences, University of Central Florida College of Medicine, Orlando, Florida, United States of America

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  • Martin Malmsten,

    Affiliation: Department of Pharmacy, Uppsala University, Uppsala, Sweden

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  • Birthe B. Kragelund,

    Affiliation: Structural Biology and NMR Laboratory, Department of Biology, University of Copenhagen, Copenhagen, Denmark

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  • Ole E. Sørensen mail

    Ole_E.Sorensen@med.lu.se

    Affiliation: Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden

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  • Published: April 05, 2012
  • DOI: 10.1371/journal.ppat.1002625

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