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Research Article

Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB

  • Hua Xiang equal contributor,

    equal contributor Contributed equally to this work with: Hua Xiang, Yue Feng

    Affiliations: Key Laboratory for Protein Sciences of Ministry of Education, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China, Department of Veterinary Pharmacology, College of Animal Science and Veterinary Medicine, Jilin University, Changchun, China

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  • Yue Feng equal contributor,

    equal contributor Contributed equally to this work with: Hua Xiang, Yue Feng

    Affiliation: Key Laboratory for Protein Sciences of Ministry of Education, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China

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  • Jiawei Wang,

    Affiliation: Key Laboratory for Protein Sciences of Ministry of Education, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China

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  • Bao Liu,

    Affiliation: Department of Vascular Surgery, Peking Union Medical College Hospital, Beijing, China

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  • Yeguang Chen,

    Affiliation: Key Laboratory for Protein Sciences of Ministry of Education, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China

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  • Lei Liu,

    Affiliations: Key Laboratory for Protein Sciences of Ministry of Education, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China, Department of Chemistry, Tsinghua University, Beijing, China

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  • Xuming Deng mail,

    xumingdeng@jluhp.edu.cn (XD); maojunyang@tsinghua.edu.cn (MY)

    Affiliation: Department of Veterinary Pharmacology, College of Animal Science and Veterinary Medicine, Jilin University, Changchun, China

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  • Maojun Yang mail

    xumingdeng@jluhp.edu.cn (XD); maojunyang@tsinghua.edu.cn (MY)

    Affiliation: Key Laboratory for Protein Sciences of Ministry of Education, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China

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  • Published: June 14, 2012
  • DOI: 10.1371/journal.ppat.1002751

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