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Research Article

The Anti-Repressor MecR2 Promotes the Proteolysis of the mecA Repressor and Enables Optimal Expression of β-lactam Resistance in MRSA

  • Pedro Arêde,

    Affiliation: CREM, Department of Life Sciences, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Caparica, Portugal

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  • Catarina Milheiriço,

    Affiliation: Laboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

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  • Hermínia de Lencastre,

    Affiliations: Laboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal, Laboratory of Microbiology and Infectious Diseases, The Rockefeller University, New York, New York, United States of America

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  • Duarte C. Oliveira mail

    dco@fct.unl.pt

    Affiliation: CREM, Department of Life Sciences, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Caparica, Portugal

    X
  • Published: July 26, 2012
  • DOI: 10.1371/journal.ppat.1002816

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