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Research Article

Humanized TLR4/MD-2 Mice Reveal LPS Recognition Differentially Impacts Susceptibility to Yersinia pestis and Salmonella enterica

  • Adeline M. Hajjar mail,

    hajjar@uw.edu

    Affiliation: Department of Comparative Medicine, University of Washington, Seattle, Washington, United States of America

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  • Robert K. Ernst equal contributor,

    equal contributor Contributed equally to this work with: Robert K. Ernst, Edgardo S. Fortuno III

    Affiliation: Department of Microbial Pathogenesis, University of Maryland, Baltimore, Maryland, United States of America

    X
  • Edgardo S. Fortuno III equal contributor,

    equal contributor Contributed equally to this work with: Robert K. Ernst, Edgardo S. Fortuno III

    Affiliation: Division of Infectious and Immunological Diseases, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Alicia S. Brasfield,

    Affiliation: Department of Comparative Medicine, University of Washington, Seattle, Washington, United States of America

    X
  • Cathy S. Yam,

    Affiliation: Department of Comparative Medicine, University of Washington, Seattle, Washington, United States of America

    X
  • Lindsay A. Newlon,

    Affiliation: Department of Immunology, University of Washington, Seattle, Washington, United States of America

    X
  • Tobias R. Kollmann,

    Affiliation: Division of Infectious and Immunological Diseases, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Samuel I. Miller,

    Affiliation: Departments of Medicine, Genome Sciences, and Microbiology, University of Washington, Seattle, Washington, United States of America

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  • Christopher B. Wilson

    Affiliation: Department of Immunology, University of Washington, Seattle, Washington, United States of America

    Current address: Bill & Melinda Gates Foundation, Seattle, Washington, United States of America

    X
  • Published: October 11, 2012
  • DOI: 10.1371/journal.ppat.1002963

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