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Research Article

Neutrophil-derived IL-1β Is Sufficient for Abscess Formation in Immunity against Staphylococcus aureus in Mice

  • John S. Cho,

    Affiliation: Department of Medicine, Division of Dermatology, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America

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  • Yi Guo,

    Affiliation: Department of Medicine, Division of Dermatology, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America

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  • Romela Irene Ramos,

    Affiliation: Department of Medicine, Division of Dermatology, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America

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  • Frank Hebroni,

    Affiliation: Department of Medicine, Division of Dermatology, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America

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  • Seema B. Plaisier,

    Affiliation: Department of Translational Immunology, Dirks/Dougherty Laboratory for Cancer Research, John Wayne Cancer Institute, Santa Monica, California, United States of America

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  • Caiyun Xuan,

    Affiliation: Department of Translational Immunology, Dirks/Dougherty Laboratory for Cancer Research, John Wayne Cancer Institute, Santa Monica, California, United States of America

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  • Jennifer L. Granick,

    Affiliation: Department of Biomedical Engineering, University of California Davis, Davis, California, United States of America

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  • Hironori Matsushima,

    Affiliation: Department of Medical Microbiology and Immunology, University of Toledo College of Medicine, Toledo, Ohio, United States of America

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  • Akira Takashima,

    Affiliation: Department of Medical Microbiology and Immunology, University of Toledo College of Medicine, Toledo, Ohio, United States of America

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  • Yoichiro Iwakura,

    Affiliation: Center for Experimental Medicine and Systems Biology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan and Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency, Saitama, Japan

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  • Ambrose L. Cheung,

    Affiliation: Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, New Hampshire, United States of America

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  • Genhong Cheng,

    Affiliation: Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America

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  • Delphine J. Lee,

    Affiliation: Department of Translational Immunology, Dirks/Dougherty Laboratory for Cancer Research, John Wayne Cancer Institute, Santa Monica, California, United States of America

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  • Scott I. Simon,

    Affiliation: Department of Biomedical Engineering, University of California Davis, Davis, California, United States of America

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  • Lloyd S. Miller mail

    lloydmiller@jhmi.edu

    Affiliation: Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Published: November 29, 2012
  • DOI: 10.1371/journal.ppat.1003047

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