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Research Article

A Structure-Guided Mutation in the Major Capsid Protein Retargets BK Polyomavirus

  • Ursula Neu equal contributor,

    equal contributor Contributed equally to this work with: Ursula Neu, Stacy-ann A. Allen

    Affiliation: Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany

    Current address: National Institute of Medical Research, The Ridgeway, Mill Hill, London, United Kingdom.

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  • Stacy-ann A. Allen equal contributor,

    equal contributor Contributed equally to this work with: Ursula Neu, Stacy-ann A. Allen

    Affiliation: Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, United States of America

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  • Bärbel S. Blaum,

    Affiliations: Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany, Department of Chemistry, University of Luebeck, Luebeck, Germany

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  • Yan Liu,

    Affiliation: Glycosciences Laboratory, Faculty of Medicine, Imperial College London, London, United Kingdom

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  • Martin Frank,

    Affiliation: Biognos AB, Gothenburg, Sweden

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  • Angelina S. Palma,

    Affiliation: Glycosciences Laboratory, Faculty of Medicine, Imperial College London, London, United Kingdom

    Current address: REQUIMTE, CQFB, Faculty of Science and Technology /UNL, Caparica, Portugal.

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  • Luisa J. Ströh,

    Affiliation: Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany

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  • Ten Feizi,

    Affiliation: Glycosciences Laboratory, Faculty of Medicine, Imperial College London, London, United Kingdom

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  • Thomas Peters,

    Affiliation: Department of Chemistry, University of Luebeck, Luebeck, Germany

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  • Walter J. Atwood mail,

    walter_atwood@brown.edu (WJA); thilo.stehle@uni-tuebingen.de (TS)

    Affiliation: Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, United States of America

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  • Thilo Stehle mail

    walter_atwood@brown.edu (WJA); thilo.stehle@uni-tuebingen.de (TS)

    Affiliations: Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Published: October 10, 2013
  • DOI: 10.1371/journal.ppat.1003688

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