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Research Article

A Model System for Studying the Transcriptomic and Physiological Changes Associated with Mammalian Host-Adaptation by Leptospira interrogans Serovar Copenhageni

  • Melissa J. Caimano mail,

    mcaima@up.uchc.edu

    Affiliations: Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut, United States of America, Department of Pediatrics, University of Connecticut Health Center, Farmington, Connecticut, United States of America

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  • Sathesh K. Sivasankaran,

    Affiliation: Department of Microbiology, School of Genetics and Microbiology, Moyne Institute of Preventative Medicine, Trinity College Dublin, Dublin, Ireland

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  • Anna Allard,

    Affiliation: Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut, United States of America

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  • Daniel Hurley,

    Affiliation: School of Veterinary Medicine, University College Dublin, Belfield, Dublin, Ireland

    Current address: UCD Centre for Food Safety, School of Public Health, Physiotherapy and Population Science, UCD Centre for Molecular Innovation and Drug Discovery, University College Dublin, Belfield, Dublin, Ireland.

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  • Karsten Hokamp,

    Affiliation: Department of Genetics, School of Genetics and Microbiology, Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland

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  • André A. Grassmann,

    Affiliations: Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut, United States of America, Unidade de Biotecnologia, Centro de Desenvolvimento Tecnológico, Universidade Federal de Pelotas, Pelotas, Rio Grande do Sul, Brazil

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  • Jay C. D. Hinton,

    Affiliations: Department of Microbiology, School of Genetics and Microbiology, Moyne Institute of Preventative Medicine, Trinity College Dublin, Dublin, Ireland, Department of Functional and Comparative Genomics, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom

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  • Jarlath E. Nally

    Affiliations: School of Veterinary Medicine, University College Dublin, Belfield, Dublin, Ireland, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland

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  • Published: March 13, 2014
  • DOI: 10.1371/journal.ppat.1004004

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