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Research Article

An Immunomics Approach to Schistosome Antigen Discovery: Antibody Signatures of Naturally Resistant and Chronically Infected Individuals from Endemic Areas

  • Soraya Gaze,

    Affiliations: Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, Queensland Tropical Health Alliance Laboratory, James Cook University, Cairns, Queensland, Australia, Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais, Centro de Pesquisas René Rachou, Instituto Fiocruz, Belo Horizonte, Minas Gerais, Brazil

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  • Patrick Driguez,

    Affiliation: QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia

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  • Mark S. Pearson,

    Affiliation: Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, Queensland Tropical Health Alliance Laboratory, James Cook University, Cairns, Queensland, Australia

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  • Tiago Mendes,

    Affiliation: Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

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  • Denise L. Doolan,

    Affiliation: QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia

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  • Angela Trieu,

    Affiliation: QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia

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  • Donald P. McManus,

    Affiliation: QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia

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  • Geoffrey N. Gobert,

    Affiliation: QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia

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  • Maria Victoria Periago,

    Affiliation: Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais, Centro de Pesquisas René Rachou, Instituto Fiocruz, Belo Horizonte, Minas Gerais, Brazil

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  • Rodrigo Correa Oliveira,

    Affiliation: Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais, Centro de Pesquisas René Rachou, Instituto Fiocruz, Belo Horizonte, Minas Gerais, Brazil

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  • Fernanda C. Cardoso,

    Affiliations: QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia, Institute for Molecular Biosciences, The University of Queensland, St Lucia, Queensland, Australia

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  • Guilherme Oliveira,

    Affiliation: Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais, Centro de Pesquisas René Rachou, Instituto Fiocruz, Belo Horizonte, Minas Gerais, Brazil

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  • Rie Nakajima,

    Affiliation: University of California Irvine, Irvine, California, United States of America

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  • Al Jasinskas,

    Affiliation: University of California Irvine, Irvine, California, United States of America

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  • Chris Hung,

    Affiliation: University of California Irvine, Irvine, California, United States of America

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  • Li Liang,

    Affiliation: University of California Irvine, Irvine, California, United States of America

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  • Jozelyn Pablo,

    Affiliation: University of California Irvine, Irvine, California, United States of America

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  • Jeffrey M. Bethony,

    Affiliation: George Washington University, Washington, D.C., United States of America

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  • Philip L. Felgner,

    Affiliation: University of California Irvine, Irvine, California, United States of America

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  • Alex Loukas mail

    Alex.Loukas@jcu.edu.au

    Affiliation: Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, Queensland Tropical Health Alliance Laboratory, James Cook University, Cairns, Queensland, Australia

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  • Published: March 27, 2014
  • DOI: 10.1371/journal.ppat.1004033

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