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Research Article

Coronavirus Non-Structural Protein 1 Is a Major Pathogenicity Factor: Implications for the Rational Design of Coronavirus Vaccines

  • Roland Züst,

    Affiliation: Research Department, Kantonal Hospital St. Gallen, St. Gallen, Switzerland

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  • Luisa Cervantes-Barragán,

    Affiliations: Research Department, Kantonal Hospital St. Gallen, St. Gallen, Switzerland, Unidad de Investigación Médica en Inmunoquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México City, México

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  • Thomas Kuri,

    Affiliation: Department of Virology, University of Freiburg, Freiburg, Germany

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  • Gjon Blakqori,

    Affiliation: Department of Virology, University of Freiburg, Freiburg, Germany

    ¤ Current address: Centre for Biomolecular Sciences, School of Biology, University of St. Andrews, North Haugh, St. Andrews, Scotland, United Kingdom

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  • Friedemann Weber,

    Affiliation: Department of Virology, University of Freiburg, Freiburg, Germany

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  • Burkhard Ludewig,

    Affiliation: Research Department, Kantonal Hospital St. Gallen, St. Gallen, Switzerland

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  • Volker Thiel mail

    To whom correspondence should be addressed. E-mail: volker.thiel@kssg.ch

    Affiliation: Research Department, Kantonal Hospital St. Gallen, St. Gallen, Switzerland

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  • Published: August 10, 2007
  • DOI: 10.1371/journal.ppat.0030109

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