# wombat urls ß PLOS Pathogens: Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages
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Research Article

Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages

  • Toshihiko Suzuki mail,

    To whom correspondence should be addressed. E-mail: t-suzuki@med.u-ryukyu.ac.jp (TS), bclx@umich.edu (GN)

    Affiliation: Division of Bacterial Pathogenesis, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan

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  • Luigi Franchi,

    Affiliation: Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Claudia Toma,

    Affiliation: Division of Bacterial Pathogenesis, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan

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  • Hiroshi Ashida,

    Affiliation: Department of Microbiology and Immunology, International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan

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  • Michinaga Ogawa,

    Affiliation: Department of Microbiology and Immunology, International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan

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  • Yuko Yoshikawa,

    Affiliation: Department of Microbiology and Immunology, International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan

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  • Hitomi Mimuro,

    Affiliation: Department of Microbiology and Immunology, International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan

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  • Naohiro Inohara,

    Affiliation: Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Chihiro Sasakawa,

    Affiliations: Department of Microbiology and Immunology, International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan, Department of Infectious Disease Control, International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Kawaguchi, Japan

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  • Gabriel Nuñez mail

    To whom correspondence should be addressed. E-mail: t-suzuki@med.u-ryukyu.ac.jp (TS), bclx@umich.edu (GN)

    Affiliation: Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Published: August 10, 2007
  • DOI: 10.1371/journal.ppat.0030111

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