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Research Article

Salp15 Binding to DC-SIGN Inhibits Cytokine Expression by Impairing both Nucleosome Remodeling and mRNA Stabilization

  • Joppe W. R Hovius equal contributor,

    equal contributor Contributed equally to this work with: Joppe W. R Hovius, Marein A. W. P de Jong

    Affiliations: Center for Experimental and Molecular Medicine, University of Amsterdam, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), University of Amsterdam, Amsterdam, The Netherlands

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  • Marein A. W. P de Jong equal contributor,

    equal contributor Contributed equally to this work with: Joppe W. R Hovius, Marein A. W. P de Jong

    Affiliation: Department of Molecular Cell Biology & Immunology, VU Medical Center, Amsterdam, The Netherlands

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  • Jeroen den Dunnen,

    Affiliation: Department of Molecular Cell Biology & Immunology, VU Medical Center, Amsterdam, The Netherlands

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  • Manja Litjens,

    Affiliation: Department of Molecular Cell Biology & Immunology, VU Medical Center, Amsterdam, The Netherlands

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  • Erol Fikrig,

    Affiliation: Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America

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  • Tom van der Poll,

    Affiliations: Center for Experimental and Molecular Medicine, University of Amsterdam, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), University of Amsterdam, Amsterdam, The Netherlands

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  • Sonja I Gringhuis,

    Affiliation: Department of Molecular Cell Biology & Immunology, VU Medical Center, Amsterdam, The Netherlands

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  • Teunis B. H Geijtenbeek mail

    To whom correspondence should be addressed. E-mail: T.Geijtenbeek@VUMC.nl

    Affiliation: Department of Molecular Cell Biology & Immunology, VU Medical Center, Amsterdam, The Netherlands

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  • Published: February 15, 2008
  • DOI: 10.1371/journal.ppat.0040031

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