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Research Article

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

  • Sven D. Willger,

    Affiliation: Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America

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  • Srisombat Puttikamonkul,

    Affiliation: Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America

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  • Kwang-Hyung Kim,

    Affiliation: Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America

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  • James B. Burritt,

    Affiliation: Department of Microbiology, Montana State University, Bozeman, Montana, United States of America

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  • Nora Grahl,

    Affiliation: Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America

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  • Laurel J. Metzler,

    Affiliation: Department of Biology, Indiana University-Purdue University, Indianapolis, Indiana, United States of America

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  • Robert Barbuch,

    Affiliation: Department of Biology, Indiana University-Purdue University, Indianapolis, Indiana, United States of America

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  • Martin Bard,

    Affiliation: Department of Biology, Indiana University-Purdue University, Indianapolis, Indiana, United States of America

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  • Christopher B. Lawrence,

    Affiliation: Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America

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  • Robert A. Cramer Jr. mail

    rcramer@montana.edu

    Affiliation: Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America

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  • Published: November 07, 2008
  • DOI: 10.1371/journal.ppat.1000200

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