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Research Article

Role of Amphipathic Helix of a Herpesviral Protein in Membrane Deformation and T Cell Receptor Downregulation

  • Chan-Ki Min,

    Affiliation: Department of Microbiology and Immunology, College of Medicine and Institute of Endemic Diseases, Seoul National University Medical Research Center and Bundang Hospital, Seoul, Korea

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  • Sun-Young Bang,

    Affiliation: Department of Microbiology and Immunology, College of Medicine and Institute of Endemic Diseases, Seoul National University Medical Research Center and Bundang Hospital, Seoul, Korea

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  • Bon-A Cho,

    Affiliation: Department of Microbiology and Immunology, College of Medicine and Institute of Endemic Diseases, Seoul National University Medical Research Center and Bundang Hospital, Seoul, Korea

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  • Yun-Hui Choi,

    Affiliation: Department of Microbiology and Immunology, College of Medicine and Institute of Endemic Diseases, Seoul National University Medical Research Center and Bundang Hospital, Seoul, Korea

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  • Jae-Seong Yang,

    Affiliation: Department of Life Science and School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, Kyungbuk, Korea

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  • Sun-Hwa Lee,

    Affiliation: Seoul National University Hospital, Innovative Research Institute for Cell Therapy, Chongno-Gu, Seoul, Korea

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  • Seung-Yong Seong,

    Affiliations: Department of Microbiology and Immunology, College of Medicine and Institute of Endemic Diseases, Seoul National University Medical Research Center and Bundang Hospital, Seoul, Korea, Seoul National University Hospital, Innovative Research Institute for Cell Therapy, Chongno-Gu, Seoul, Korea

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  • Ki Woo Kim,

    Affiliation: National Instrumentation Center for Environmental Management, Seoul National University, Gwanak-Gu, Seoul, Korea

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  • Sanguk Kim,

    Affiliation: Department of Life Science and School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, Kyungbuk, Korea

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  • Jae Ung Jung,

    Affiliation: Department of Molecular Microbiology and Immunology, University of Southern California School of Medicine, Los Angeles, California, United States of America

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  • Myung-Sik Choi,

    Affiliation: Department of Microbiology and Immunology, College of Medicine and Institute of Endemic Diseases, Seoul National University Medical Research Center and Bundang Hospital, Seoul, Korea

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  • Ik-Sang Kim,

    Affiliation: Department of Microbiology and Immunology, College of Medicine and Institute of Endemic Diseases, Seoul National University Medical Research Center and Bundang Hospital, Seoul, Korea

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  • Nam-Hyuk Cho mail

    chonh@snu.ac.kr

    Affiliation: Department of Microbiology and Immunology, College of Medicine and Institute of Endemic Diseases, Seoul National University Medical Research Center and Bundang Hospital, Seoul, Korea

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  • Published: November 21, 2008
  • DOI: 10.1371/journal.ppat.1000209

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