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Research Article

The Glutathione Biosynthetic Pathway of Plasmodium Is Essential for Mosquito Transmission

  • Joel Vega-Rodríguez,

    Affiliation: Department of Microbiology and Medical Zoology, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico

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  • Blandine Franke-Fayard equal contributor,

    equal contributor Contributed equally to this work with: Blandine Franke-Fayard, Rhoel R. Dinglasan

    Affiliation: Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands

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  • Rhoel R. Dinglasan equal contributor,

    equal contributor Contributed equally to this work with: Blandine Franke-Fayard, Rhoel R. Dinglasan

    Affiliation: Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, United States of America

    X
  • Chris J. Janse,

    Affiliation: Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands

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  • Rebecca Pastrana-Mena,

    Affiliation: Department of Microbiology and Medical Zoology, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico

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  • Andrew P. Waters,

    Affiliations: Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands, Wellcome Trust Centre of Molecular Parasitology and Division of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom

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  • Isabelle Coppens,

    Affiliation: Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, United States of America

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  • José F. Rodríguez-Orengo,

    Affiliation: Department of Biochemistry, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico

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  • Marcelo Jacobs-Lorena,

    Affiliation: Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, United States of America

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  • Adelfa E. Serrano mail

    adelfa.serrano@upr.edu

    Affiliation: Department of Microbiology and Medical Zoology, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico

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  • Published: February 20, 2009
  • DOI: 10.1371/journal.ppat.1000302

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