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Research Article

The Urokinase Receptor (uPAR) Facilitates Clearance of Borrelia burgdorferi

  • Joppe W. R. Hovius mail,

    j.w.hovius@amc.uva.nl

    Affiliations: Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands, Department of Medicine, Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • Maarten F. Bijlsma,

    Affiliations: Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • Gerritje J. W. van der Windt,

    Affiliations: Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • W. Joost Wiersinga,

    Affiliations: Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands, Department of Medicine, Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • Bastiaan J. D. Boukens,

    Affiliation: Heart Failure Research Center, Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • Jeroen Coumou,

    Affiliation: Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • Anneke Oei,

    Affiliation: Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • Regina de Beer,

    Affiliations: Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • Alex F. de Vos,

    Affiliations: Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • Cornelis van 't Veer,

    Affiliations: Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • Alje P. van Dam,

    Affiliation: Onze Lieve Vrouwe Gasthuis, Department of Medical Microbiology, Amsterdam, The Netherlands

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  • Penghua Wang,

    Affiliation: Yale University, School of Medicine, Section of Infectious Diseases, Department of Internal Medicine, New Haven, Connecticut, United States of America

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  • Erol Fikrig,

    Affiliation: Yale University, School of Medicine, Section of Infectious Diseases, Department of Internal Medicine, New Haven, Connecticut, United States of America

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  • Marcel M. Levi,

    Affiliation: Department of Medicine, Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • Joris J. T. H. Roelofs,

    Affiliation: Department of Pathology, Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • Tom van der Poll

    Affiliations: Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands, Department of Medicine, Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands

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  • Published: May 22, 2009
  • DOI: 10.1371/journal.ppat.1000447

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