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Research Article

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking

  • Richard S. Mitchell,

    Affiliation: Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • Chris Katsura,

    Affiliation: Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • Mark A. Skasko,

    Affiliation: Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • Katie Fitzpatrick,

    Affiliation: Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • David Lau,

    Affiliation: Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • Autumn Ruiz,

    Affiliation: Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas, United States of America

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  • Edward B. Stephens,

    Affiliation: Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas, United States of America

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  • Florence Margottin-Goguet,

    Affiliations: Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France, Inserm, U567, Paris, France

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  • Richard Benarous,

    Affiliation: CellVir, Genopole, Evry, France

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  • John C. Guatelli mail

    jguatelli@ucsd.edu

    Affiliations: Department of Medicine, University of California San Diego, La Jolla, California, United States of America, San Diego Veterans Affairs Healthcare System, San Diego, California, United States of America

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  • Published: May 29, 2009
  • DOI: 10.1371/journal.ppat.1000450

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