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Research Article

Comparative Genomic Characterization of Francisella tularensis Strains Belonging to Low and High Virulence Subspecies

  • Mia D. Champion equal contributor mail,

    equal contributor Contributed equally to this work with: Mia D. Champion, Qiandong Zeng

    champion@broad.mit.edu

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Qiandong Zeng equal contributor,

    equal contributor Contributed equally to this work with: Mia D. Champion, Qiandong Zeng

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Eli B. Nix,

    Affiliation: Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

    X
  • Francis E. Nano,

    Affiliation: Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

    X
  • Paul Keim,

    Affiliations: Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, United States of America, Pathogen Genomics Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America

    X
  • Chinnappa D. Kodira,

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Mark Borowsky,

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Sarah Young,

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Michael Koehrsen,

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Reinhard Engels,

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Matthew Pearson,

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Clint Howarth,

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Lisa Larson,

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Jared White,

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Lucia Alvarado,

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Mats Forsman,

    Affiliation: Department of CBRN Defense and Security, Swedish Defense Research Agency, Umeå, Sweden

    X
  • Scott W. Bearden,

    Affiliation: Centers for Disease Control and Prevention, Division of Vector-Borne Infectious Diseases, Fort Collins, Colorado, United States of America

    X
  • Anders Sjöstedt,

    Affiliation: Department of Clinical Bacteriology, Clinical Microbiology, Umeå University, Umeå, Sweden

    X
  • Richard Titball,

    Affiliation: University of Exeter, School of Biosciences, Exeter, United Kingdom

    X
  • Stephen L. Michell,

    Affiliation: University of Exeter, School of Biosciences, Exeter, United Kingdom

    X
  • Bruce Birren,

    Affiliation: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • James Galagan

    Affiliations: Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Boston University Department of Biomedical Engineering and the Boston University Medical School, Boston, Massachusetts, United States of America

    X
  • Published: May 29, 2009
  • DOI: 10.1371/journal.ppat.1000459

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