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Research Article

Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

  • Artur Kaul,

    Affiliation: Department of Molecular Virology, University of Heidelberg, Heidelberg, Germany

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  • Sarah Stauffer equal contributor,

    equal contributor Contributed equally to this work with: Sarah Stauffer, Carola Berger

    Affiliation: Department of Molecular Virology, University of Heidelberg, Heidelberg, Germany

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  • Carola Berger equal contributor,

    equal contributor Contributed equally to this work with: Sarah Stauffer, Carola Berger

    Affiliation: Department of Molecular Virology, University of Heidelberg, Heidelberg, Germany

    X
  • Thomas Pertel,

    Affiliation: Department of Microbiology and Molecular Medicine, University of Geneva, Geneva, Switzerland

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  • Jennifer Schmitt,

    Affiliation: Department of Molecular Virology, University of Heidelberg, Heidelberg, Germany

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  • Stephanie Kallis,

    Affiliation: Department of Molecular Virology, University of Heidelberg, Heidelberg, Germany

    X
  • Margarita Zayas Lopez,

    Affiliation: Department of Molecular Virology, University of Heidelberg, Heidelberg, Germany

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  • Volker Lohmann,

    Affiliation: Department of Molecular Virology, University of Heidelberg, Heidelberg, Germany

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  • Jeremy Luban,

    Affiliation: Department of Microbiology and Molecular Medicine, University of Geneva, Geneva, Switzerland

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  • Ralf Bartenschlager mail

    Ralf_Bartenschlager@med.uni-heidelberg.de

    Affiliation: Department of Molecular Virology, University of Heidelberg, Heidelberg, Germany

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  • Published: August 14, 2009
  • DOI: 10.1371/journal.ppat.1000546

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