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Research Article

Bacterial Porin Disrupts Mitochondrial Membrane Potential and Sensitizes Host Cells to Apoptosis

  • Vera Kozjak-Pavlovic equal contributor,

    equal contributor Contributed equally to this work with: Vera Kozjak-Pavlovic, Elke A. Dian-Lothrop, Michael Meinecke, Oliver Kepp

    Affiliations: Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany, Biocenter, Chair of Microbiology, University of Würzburg, Würzburg, Germany

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  • Elke A. Dian-Lothrop equal contributor,

    equal contributor Contributed equally to this work with: Vera Kozjak-Pavlovic, Elke A. Dian-Lothrop, Michael Meinecke, Oliver Kepp

    Affiliation: Institute for Physiological Chemistry, Ruhr-University Bochum, Bochum, Germany

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  • Michael Meinecke equal contributor,

    equal contributor Contributed equally to this work with: Vera Kozjak-Pavlovic, Elke A. Dian-Lothrop, Michael Meinecke, Oliver Kepp

    Affiliation: Department of Biology/Chemistry, Division of Biophysics, University of Osnabrück, Osnabrück, Germany

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  • Oliver Kepp equal contributor,

    equal contributor Contributed equally to this work with: Vera Kozjak-Pavlovic, Elke A. Dian-Lothrop, Michael Meinecke, Oliver Kepp

    Affiliation: Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany

    Current address: INSERM U848, Institut Gustav Roussy, Faculté Sud-Université Paris 11, Villejuif, France

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  • Katharina Ross,

    Affiliation: Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany

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  • Krishnaraj Rajalingam,

    Affiliation: Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany

    Current address: Emmy Noether Group of DFG, Institut für Biochemie II, Goethe University Medical School, Frankfurt, Germany

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  • Anke Harsman,

    Affiliation: Protein Purification Core Facility, Max Planck Institute for Infection Biology, Berlin, Germany

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  • Eva Hauf,

    Affiliation: Microscopy Core Facility, Max Planck Institute for Infection Biology, Berlin, Germany

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  • Volker Brinkmann,

    Affiliation: Microscopy Core Facility, Max Planck Institute for Infection Biology, Berlin, Germany

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  • Dirk Günther,

    Affiliation: Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany

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  • Ines Herrmann,

    Affiliation: Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany

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  • Robert Hurwitz,

    Affiliation: Protein Purification Core Facility, Max Planck Institute for Infection Biology, Berlin, Germany

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  • Joachim Rassow,

    Affiliation: Institute for Physiological Chemistry, Ruhr-University Bochum, Bochum, Germany

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  • Richard Wagner,

    Affiliation: Department of Biology/Chemistry, Division of Biophysics, University of Osnabrück, Osnabrück, Germany

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  • Thomas Rudel mail

    thomas.rudel@biozentrum.uni-wuerzburg.de

    Affiliations: Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany, Biocenter, Chair of Microbiology, University of Würzburg, Würzburg, Germany

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  • Published: October 23, 2009
  • DOI: 10.1371/journal.ppat.1000629

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