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Research Article

Glypican-1 Mediates Both Prion Protein Lipid Raft Association and Disease Isoform Formation

  • David R. Taylor,

    Affiliation: Proteolysis Research Group, Institute of Molecular and Cellular Biology, Faculty of Biological Sciences, and Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, United Kingdom

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  • Isobel J. Whitehouse,

    Affiliation: Proteolysis Research Group, Institute of Molecular and Cellular Biology, Faculty of Biological Sciences, and Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, United Kingdom

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  • Nigel M. Hooper mail

    n.m.hooper@leeds.ac.uk

    Affiliation: Proteolysis Research Group, Institute of Molecular and Cellular Biology, Faculty of Biological Sciences, and Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, United Kingdom

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  • Published: November 20, 2009
  • DOI: 10.1371/journal.ppat.1000666

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