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Research Article

Antagonism of Tetherin Restriction of HIV-1 Release by Vpu Involves Binding and Sequestration of the Restriction Factor in a Perinuclear Compartment

  • Mathieu Dubé,

    Affiliation: Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada

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  • Bibhuti Bhusan Roy,

    Affiliation: Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada

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  • Pierre Guiot-Guillain,

    Affiliation: Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada

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  • Julie Binette,

    Affiliation: Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada

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  • Johanne Mercier,

    Affiliation: Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada

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  • Antoine Chiasson,

    Affiliation: Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada

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  • Éric A. Cohen mail

    eric.cohen@ircm.qc.ca

    Affiliations: Laboratory of Human Retrovirology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada, Department of Microbiology and Immunology, Université de Montréal, Montreal, Quebec, Canada

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  • Published: April 08, 2010
  • DOI: 10.1371/journal.ppat.1000856

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