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Research Article

Leprosy and the Adaptation of Human Toll-Like Receptor 1

  • Sunny H. Wong,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Sailesh Gochhait,

    Affiliation: National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India

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  • Dheeraj Malhotra,

    Affiliation: National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India

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  • Fredrik H. Pettersson,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Yik Y. Teo,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Chiea C. Khor,

    Affiliations: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Host Susceptibility to Infection Program, Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore

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  • Anna Rautanen,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Stephen J. Chapman,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Tara C. Mills,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Amit Srivastava,

    Affiliation: National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India

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  • Aleksey Rudko,

    Affiliation: Research Institute of Medical Genetics, Siberian Branch of Russian Academy of Medical Sciences, Tomsk, Russia

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  • Maxim B. Freidin,

    Affiliations: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Research Institute of Medical Genetics, Siberian Branch of Russian Academy of Medical Sciences, Tomsk, Russia

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  • Valery P. Puzyrev,

    Affiliation: Research Institute of Medical Genetics, Siberian Branch of Russian Academy of Medical Sciences, Tomsk, Russia

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  • Shafat Ali,

    Affiliation: National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India

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  • Shweta Aggarwal,

    Affiliation: National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India

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  • Rupali Chopra,

    Affiliation: National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India

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  • Belum S. N. Reddy,

    Affiliation: Department of Dermatology and Sexually Transmitted Diseases, Maulana Azad Medical College, Lok Nayak Jai Prakash Hospital, New Delhi, India

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  • Vijay K. Garg,

    Affiliation: Department of Dermatology and Sexually Transmitted Diseases, Maulana Azad Medical College, Lok Nayak Jai Prakash Hospital, New Delhi, India

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  • Suchismita Roy,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Sarah Meisner,

    Affiliation: Bath Royal United Hospital Trust, Combe Park, Bath, United Kingdom

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  • Sunil K. Hazra,

    Affiliation: Calcutta School of Tropical Medicine, Kolkata, India

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  • Bibhuti Saha,

    Affiliation: Calcutta School of Tropical Medicine, Kolkata, India

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  • Sian Floyd,

    Affiliation: Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom

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  • Brendan J. Keating,

    Affiliation: Institute for Translational Medicine and Therapeutics, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Cecilia Kim,

    Affiliation: Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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  • Benjamin P. Fairfax,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Julian C. Knight,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Philip C. Hill,

    Affiliation: MRC Laboratories, Fajara, The Gambia

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  • Richard A. Adegbola,

    Affiliation: MRC Laboratories, Fajara, The Gambia

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  • Hakon Hakonarson,

    Affiliation: Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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  • Paul E. M. Fine,

    Affiliation: Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom

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  • Ramasamy M. Pitchappan,

    Affiliation: Centre for Excellence in Genomic Sciences, Madurai Kamaraj University, Madurai, India

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  • Rameshwar N. K. Bamezai,

    Affiliation: National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India

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  • Adrian V. S. Hill,

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Fredrik O. Vannberg mail

    vannberg@well.ox.ac.uk

    Affiliation: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Published: July 01, 2010
  • DOI: 10.1371/journal.ppat.1000979

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