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Research Article

Early Severe Inflammatory Responses to Uropathogenic E. coli Predispose to Chronic and Recurrent Urinary Tract Infection

  • Thomas J. Hannan,

    Affiliations: Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Indira U. Mysorekar,

    Affiliations: Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Chia S. Hung,

    Affiliation: Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Megan L. Isaacson-Schmid,

    Affiliation: Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Scott J. Hultgren mail

    hultgren@borcim.wustl.edu

    Affiliation: Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Published: August 12, 2010
  • DOI: 10.1371/journal.ppat.1001042

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