Advertisement
Research Article

Viral Replication Rate Regulates Clinical Outcome and CD8 T Cell Responses during Highly Pathogenic H5N1 Influenza Virus Infection in Mice

  • Yasuko Hatta equal contributor,

    equal contributor Contributed equally to this work with: Yasuko Hatta, Karen Hershberger

    Affiliations: Influenza Research Institute, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

    X
  • Karen Hershberger equal contributor,

    equal contributor Contributed equally to this work with: Yasuko Hatta, Karen Hershberger

    Affiliations: Influenza Research Institute, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

    X
  • Kyoko Shinya,

    Affiliation: Division of Zoonosis, Department of Microbiology and Infectious Disease, Graduate School of Medicine, Kobe University, Kusunoki-cho, Chuo-ku, Kobe, Hyogo, Japan

    X
  • Sean C. Proll,

    Affiliation: Department of Microbiology, School of Medicine, University of Washington, Seattle, Washington, United States of America

    X
  • Richard R. Dubielzig,

    Affiliation: Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

    X
  • Masato Hatta,

    Affiliations: Influenza Research Institute, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

    X
  • Michael G. Katze,

    Affiliation: Department of Microbiology, School of Medicine, University of Washington, Seattle, Washington, United States of America

    X
  • Yoshihiro Kawaoka mail,

    sureshm@svm.vetmed.wisc.edu (MS); kawaokay@svm.vetmed.wisc.edu (YK)

    Affiliations: Influenza Research Institute, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Division of Virology, Department of Microbiology and Immunology and International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan

    X
  • M. Suresh mail

    sureshm@svm.vetmed.wisc.edu (MS); kawaokay@svm.vetmed.wisc.edu (YK)

    Affiliations: Influenza Research Institute, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

    X
  • Published: October 07, 2010
  • DOI: 10.1371/journal.ppat.1001139

Viewed info

Cited info

Saved info

Discussed info

Questions or concerns about usage data? Please let us know.