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Research Article

Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium

  • Louise Slater,

    Affiliations: Department of Respiratory Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Centre for Respiratory Infection, London, United Kingdom

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  • Nathan W. Bartlett,

    Affiliations: Department of Respiratory Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Centre for Respiratory Infection, London, United Kingdom

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  • Jennifer J. Haas,

    Affiliations: Department of Respiratory Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Centre for Respiratory Infection, London, United Kingdom

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  • Jie Zhu,

    Affiliation: Lung Pathology, National Heart & Lung Institute, Imperial College London, London, United Kingdom

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  • Simon D. Message,

    Affiliations: Department of Respiratory Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom, Imperial Healthcare NHS Trust, London, United Kingdom

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  • Ross P. Walton,

    Affiliations: Department of Respiratory Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Centre for Respiratory Infection, London, United Kingdom

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  • Annemarie Sykes,

    Affiliations: Department of Respiratory Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Centre for Respiratory Infection, London, United Kingdom, Imperial Healthcare NHS Trust, London, United Kingdom

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  • Samer Dahdaleh,

    Affiliation: Department of Respiratory Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom

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  • Deborah L. Clarke,

    Affiliations: Centre for Respiratory Infection, London, United Kingdom, Respiratory Pharmacology, National Heart & Lung Institute, Imperial College London, London, United Kingdom

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  • Maria G. Belvisi,

    Affiliations: Centre for Respiratory Infection, London, United Kingdom, Respiratory Pharmacology, National Heart & Lung Institute, Imperial College London, London, United Kingdom

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  • Onn M. Kon,

    Affiliations: Centre for Respiratory Infection, London, United Kingdom, Imperial Healthcare NHS Trust, London, United Kingdom

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  • Takashi Fujita,

    Affiliation: Institute of Virus Research, Kyoto University, Kyoto, Japan

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  • Peter K. Jeffery,

    Affiliation: Lung Pathology, National Heart & Lung Institute, Imperial College London, London, United Kingdom

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  • Sebastian L. Johnston,

    Affiliations: Department of Respiratory Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Centre for Respiratory Infection, London, United Kingdom, Imperial Healthcare NHS Trust, London, United Kingdom

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  • Michael R. Edwards mail

    michael.edwards@imperial.ac.uk

    Affiliations: Department of Respiratory Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom, Centre for Respiratory Infection, London, United Kingdom

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  • Published: November 04, 2010
  • DOI: 10.1371/journal.ppat.1001178

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