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Research Article

Dual Chaperone Role of the C-Terminal Propeptide in Folding and Oligomerization of the Pore-Forming Toxin Aerolysin

  • Ioan Iacovache equal contributor,

    equal contributor Contributed equally to this work with: Ioan Iacovache, Matteo T. Degiacomi

    Affiliation: Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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  • Matteo T. Degiacomi equal contributor,

    equal contributor Contributed equally to this work with: Ioan Iacovache, Matteo T. Degiacomi

    Affiliation: Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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  • Lucile Pernot,

    Affiliation: Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

    Current address: Pharmaceutical Biochemistry Group, School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland

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  • Sylvia Ho,

    Affiliation: Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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  • Marc Schiltz,

    Affiliation: Laboratoire de Cristallographie, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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  • Matteo Dal Peraro mail,

    gisou.vandergoot@epfl.ch (FGVDH); matteo.dalperaro@epfl.ch (MDP)

    Affiliation: Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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  • F. Gisou van der Goot mail

    gisou.vandergoot@epfl.ch (FGVDH); matteo.dalperaro@epfl.ch (MDP)

    Affiliation: Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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  • Published: July 14, 2011
  • DOI: 10.1371/journal.ppat.1002135

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