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Research Article

Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim / Mcl-1 Imbalance

  • Maikel L. Colli,

    Affiliation: Laboratory of Experimental Medicine, Medical Faculty, Université Libre de Bruxelles, Brussels, Belgium

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  • Tatiane C. Nogueira,

    Affiliation: Laboratory of Experimental Medicine, Medical Faculty, Université Libre de Bruxelles, Brussels, Belgium

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  • Florent Allagnat,

    Affiliation: Laboratory of Experimental Medicine, Medical Faculty, Université Libre de Bruxelles, Brussels, Belgium

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  • Daniel A. Cunha,

    Affiliation: Laboratory of Experimental Medicine, Medical Faculty, Université Libre de Bruxelles, Brussels, Belgium

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  • Esteban N. Gurzov,

    Affiliation: Laboratory of Experimental Medicine, Medical Faculty, Université Libre de Bruxelles, Brussels, Belgium

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  • Alessandra K. Cardozo,

    Affiliation: Laboratory of Experimental Medicine, Medical Faculty, Université Libre de Bruxelles, Brussels, Belgium

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  • Merja Roivainen,

    Affiliation: Intestinal Viruses Unit, Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare (THL), Helsinki, Finland

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  • Anne Op de beeck,

    Affiliation: Virology Unit, Medical Faculty, Université Libre de Bruxelles, Brussels, Belgium

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  • Decio L. Eizirik mail

    deizirik@ulb.ac.be

    Affiliation: Laboratory of Experimental Medicine, Medical Faculty, Université Libre de Bruxelles, Brussels, Belgium

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  • Published: September 22, 2011
  • DOI: 10.1371/journal.ppat.1002267

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