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Research Article

CNS Recruitment of CD8+ T Lymphocytes Specific for a Peripheral Virus Infection Triggers Neuropathogenesis during Polymicrobial Challenge

  • Christine M. Matullo,

    Affiliations: Fox Chase Cancer Center, Division of Basic Science, Program in Immune Cell Development and Host Defense, Philadelphia, Pennsylvania, United States of America, Thomas Jefferson University, Department of Microbiology and Immunology, Philadelphia, Pennsylvania, United States of America

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  • Kevin J. O'Regan,

    Affiliation: Fox Chase Cancer Center, Division of Basic Science, Program in Immune Cell Development and Host Defense, Philadelphia, Pennsylvania, United States of America

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  • Mark Curtis,

    Affiliation: Thomas Jefferson University, Department of Pathology, Anatomy, and Cell Biology, Philadelphia, Pennsylvania, United States of America

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  • Glenn F. Rall mail

    glenn.rall@fccc.edu

    Affiliation: Fox Chase Cancer Center, Division of Basic Science, Program in Immune Cell Development and Host Defense, Philadelphia, Pennsylvania, United States of America

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  • Published: December 22, 2011
  • DOI: 10.1371/journal.ppat.1002462

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