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Research Article

Calcium Influx Rescues Adenylate Cyclase-Hemolysin from Rapid Cell Membrane Removal and Enables Phagocyte Permeabilization by Toxin Pores

  • Radovan Fiser equal contributor,

    equal contributor Contributed equally to this work with: Radovan Fiser, Jiri Masin

    Affiliations: Faculty of Science, Charles University, Prague, Czech Republic, Institute of Microbiology of the ASCR, v.v.i., Prague, Czech Republic

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  • Jiri Masin equal contributor,

    equal contributor Contributed equally to this work with: Radovan Fiser, Jiri Masin

    Affiliation: Institute of Microbiology of the ASCR, v.v.i., Prague, Czech Republic

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  • Ladislav Bumba,

    Affiliation: Institute of Microbiology of the ASCR, v.v.i., Prague, Czech Republic

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  • Eva Pospisilova,

    Affiliation: Institute of Microbiology of the ASCR, v.v.i., Prague, Czech Republic

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  • Catherine Fayolle,

    Affiliations: Institut Pasteur, Paris, France, INSERM U1041, Paris, France

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  • Marek Basler,

    Affiliation: Institute of Microbiology of the ASCR, v.v.i., Prague, Czech Republic

    Current address: Harvard Medical School, Boston, Massachusetts, United States of America

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  • Lenka Sadilkova,

    Affiliation: Institute of Microbiology of the ASCR, v.v.i., Prague, Czech Republic

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  • Irena Adkins,

    Affiliation: Institute of Microbiology of the ASCR, v.v.i., Prague, Czech Republic

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  • Jana Kamanova,

    Affiliation: Institute of Microbiology of the ASCR, v.v.i., Prague, Czech Republic

    Current address: Yale Medical School, New Haven, Connecticut, United States of America

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  • Jan Cerny,

    Affiliation: Faculty of Science, Charles University, Prague, Czech Republic

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  • Ivo Konopasek,

    Affiliation: Faculty of Science, Charles University, Prague, Czech Republic

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  • Radim Osicka,

    Affiliation: Institute of Microbiology of the ASCR, v.v.i., Prague, Czech Republic

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  • Claude Leclerc,

    Affiliations: Institut Pasteur, Paris, France, INSERM U1041, Paris, France

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  • Peter Sebo mail

    sebo@biomed.cas.cz

    Affiliations: Institute of Microbiology of the ASCR, v.v.i., Prague, Czech Republic, Institute of Biotechnology of the ASCR, v.v.i., Prague, Czech Republic

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  • Published: April 05, 2012
  • DOI: 10.1371/journal.ppat.1002580

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