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Research Article

The Exopolysaccharide Matrix Modulates the Interaction between 3D Architecture and Virulence of a Mixed-Species Oral Biofilm

  • Jin Xiao,

    Affiliations: Center for Oral Biology, University of Rochester Medical Center, Rochester, New York, United States of America, State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China

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  • Marlise I. Klein,

    Affiliation: Center for Oral Biology, University of Rochester Medical Center, Rochester, New York, United States of America

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  • Megan L. Falsetta,

    Affiliation: Center for Oral Biology, University of Rochester Medical Center, Rochester, New York, United States of America

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  • Bingwen Lu,

    Affiliation: Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Claire M. Delahunty,

    Affiliation: Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America

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  • John R. Yates III,

    Affiliation: Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Arne Heydorn,

    Affiliation: Department of General Medicine, Glostrup Hospital, Glostrup, Denmark

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  • Hyun Koo mail

    Hyun_Koo@urmc.rochester.edu

    Affiliations: Center for Oral Biology, University of Rochester Medical Center, Rochester, New York, United States of America, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America

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  • Published: April 05, 2012
  • DOI: 10.1371/journal.ppat.1002623

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