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Research Article

Evolution of Salmonella enterica Virulence via Point Mutations in the Fimbrial Adhesin

  • Dagmara I. Kisiela,

    Affiliation: Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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  • Sujay Chattopadhyay,

    Affiliation: Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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  • Stephen J. Libby,

    Affiliation: Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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  • Joyce E. Karlinsey,

    Affiliation: Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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  • Ferric C. Fang,

    Affiliation: Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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  • Veronika Tchesnokova,

    Affiliation: Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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  • Jeremy J. Kramer,

    Affiliation: Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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  • Viktoriya Beskhlebnaya,

    Affiliation: Institute for Environmental Health, Lake Forest Park, Washington, United States of America

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  • Mansour Samadpour,

    Affiliation: Institute for Environmental Health, Lake Forest Park, Washington, United States of America

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  • Krzysztof Grzymajlo,

    Affiliation: Department of Biochemistry, Pharmacology and Toxicology, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland

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  • Maciej Ugorski,

    Affiliation: Department of Biochemistry, Pharmacology and Toxicology, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland

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  • Emily W. Lankau,

    Affiliation: Department of Animal Sciences, University of Illinois, Urbana, Illinois, United States of America

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  • Roderick I. Mackie,

    Affiliation: Department of Animal Sciences, University of Illinois, Urbana, Illinois, United States of America

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  • Steven Clegg,

    Affiliation: Department of Microbiology, University of Iowa, Iowa City, Iowa, United States of America

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  • Evgeni V. Sokurenko mail

    evs@u.washington.edu

    Affiliation: Department of Microbiology, University of Washington, Seattle, Washington, United States of America

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  • Published: June 07, 2012
  • DOI: 10.1371/journal.ppat.1002733

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