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Research Article

Identification of Site-Specific Adaptations Conferring Increased Neural Cell Tropism during Human Enterovirus 71 Infection

  • Samuel Cordey equal contributor mail,

    equal contributor Contributed equally to this work with: Samuel Cordey, Tom J. Petty

    samuel.cordey@hcuge.ch

    Affiliations: Laboratory of Virology, Division of Infectious Diseases and Division of Laboratory Medicine, University Hospitals of Geneva, Geneva, Switzerland, Department of Medicine, University of Geneva Medical School, Geneva, Switzerland

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  • Tom J. Petty equal contributor,

    equal contributor Contributed equally to this work with: Samuel Cordey, Tom J. Petty

    Affiliations: Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Swiss Institute of Bioinformatics, Geneva, Switzerland

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  • Manuel Schibler,

    Affiliations: Laboratory of Virology, Division of Infectious Diseases and Division of Laboratory Medicine, University Hospitals of Geneva, Geneva, Switzerland, Department of Medicine, University of Geneva Medical School, Geneva, Switzerland

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  • Yannick Martinez,

    Affiliation: Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland

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  • Daniel Gerlach,

    Affiliation: Research Institute of Molecular Pathology (IMP), Vienna, Austria

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  • Sandra van Belle,

    Affiliations: Laboratory of Virology, Division of Infectious Diseases and Division of Laboratory Medicine, University Hospitals of Geneva, Geneva, Switzerland, Department of Medicine, University of Geneva Medical School, Geneva, Switzerland

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  • Lara Turin,

    Affiliations: Laboratory of Virology, Division of Infectious Diseases and Division of Laboratory Medicine, University Hospitals of Geneva, Geneva, Switzerland, Department of Medicine, University of Geneva Medical School, Geneva, Switzerland

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  • Evgeny Zdobnov,

    Affiliations: Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Swiss Institute of Bioinformatics, Geneva, Switzerland, Imperial College London, South Kensington Campus, London, United Kingdom

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  • Laurent Kaiser ,

    Affiliations: Laboratory of Virology, Division of Infectious Diseases and Division of Laboratory Medicine, University Hospitals of Geneva, Geneva, Switzerland, Department of Medicine, University of Geneva Medical School, Geneva, Switzerland

    These authors also contributed equally to this work.

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  • Caroline Tapparel

    Affiliations: Laboratory of Virology, Division of Infectious Diseases and Division of Laboratory Medicine, University Hospitals of Geneva, Geneva, Switzerland, Department of Medicine, University of Geneva Medical School, Geneva, Switzerland

    These authors also contributed equally to this work.

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  • Published: July 26, 2012
  • DOI: 10.1371/journal.ppat.1002826

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