Advertisement
Research Article

Self-Enhancement of Hepatitis C Virus Replication by Promotion of Specific Sphingolipid Biosynthesis

  • Yuichi Hirata,

    Affiliation: Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan

    X
  • Kazutaka Ikeda,

    Affiliations: Department of Metabolome, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan, Institute for Advanced Biosciences, Keio University, Kakuganji, Tsuruoka, Yamagata, Japan

    X
  • Masayuki Sudoh,

    Affiliation: Kamakura Research Laboratories, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa, Japan

    X
  • Yuko Tokunaga,

    Affiliation: Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan

    X
  • Akemi Suzuki,

    Affiliation: Institute of Glycoscience, Tokai University, Hiratsuka-shi, Kanagawa, Japan

    X
  • Leiyun Weng,

    Affiliation: Unit of Viral Genome Regulation, Institut Pasteur of Shanghai, Key Laboratory of Molecular Virology & Immunology, Chinese Academy of Sciences, Shanghai, China

    X
  • Masatoshi Ohta,

    Affiliation: Institute for Advanced Biosciences, Keio University, Kakuganji, Tsuruoka, Yamagata, Japan

    X
  • Yoshimi Tobita,

    Affiliation: Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan

    X
  • Ken Okano,

    Affiliation: Fuji-Gotemba Research Laboratories, Chugai Pharmaceutical Co., Ltd., Gotemba, Shizuoka, Japan

    X
  • Kazuhisa Ozeki,

    Affiliation: Fuji-Gotemba Research Laboratories, Chugai Pharmaceutical Co., Ltd., Gotemba, Shizuoka, Japan

    X
  • Kenichi Kawasaki,

    Affiliation: Kamakura Research Laboratories, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa, Japan

    X
  • Takuo Tsukuda,

    Affiliation: Kamakura Research Laboratories, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa, Japan

    X
  • Asao Katsume,

    Affiliation: Kamakura Research Laboratories, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa, Japan

    X
  • Yuko Aoki,

    Affiliation: Kamakura Research Laboratories, Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa, Japan

    X
  • Takuya Umehara,

    Affiliation: Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan

    X
  • Satoshi Sekiguchi,

    Affiliation: Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan

    X
  • Tetsuya Toyoda,

    Affiliation: Unit of Viral Genome Regulation, Institut Pasteur of Shanghai, Key Laboratory of Molecular Virology & Immunology, Chinese Academy of Sciences, Shanghai, China

    X
  • Kunitada Shimotohno,

    Affiliation: Research Institute, Chiba Institute of Technology, Narashino, Chiba, Japan

    X
  • Tomoyoshi Soga,

    Affiliation: Institute for Advanced Biosciences, Keio University, Kakuganji, Tsuruoka, Yamagata, Japan

    X
  • Masahiro Nishijima,

    Affiliations: National Institute of Health Sciences, Setagaya-ku, Tokyo, Japan, Showa Pharmaceutical University, Machidashi, Tokyo, Japan

    X
  • Ryo Taguchi,

    Affiliations: Department of Metabolome, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan, Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai-shi, Aichi, Japan

    X
  • Michinori Kohara mail

    kohara-mc@igakuken.or.jp

    Affiliation: Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan

    X
  • Published: August 16, 2012
  • DOI: 10.1371/journal.ppat.1002860

Viewed info

Cited info

Saved info

Discussed info

Questions or concerns about usage data? Please let us know.