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Research Article

Unbiased Mutagenesis of MHV68 LANA Reveals a DNA-Binding Domain Required for LANA Function In Vitro and In Vivo

  • Clinton R. Paden,

    Affiliations: Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America, Immunology and Molecular Pathogenesis Graduate Program, Emory University, Atlanta, Georgia, United States of America

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  • J. Craig Forrest,

    Affiliation: Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America

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  • Scott A. Tibbetts,

    Affiliation: Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, Florida, United States of America

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  • Samuel H. Speck mail

    sspeck@emory.edu

    Affiliation: Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • Published: September 06, 2012
  • DOI: 10.1371/journal.ppat.1002906

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