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Research Article

NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis

  • Gerben Ferwerda,

    Affiliations: Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands, Nijmegen University Center for Infectious Diseases, Nijmegen, The Netherlands

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  • Stephen E Girardin,

    Affiliation: Unité de Pathogénie Microbienne Moléculaire, INSERM U389, Institut Pasteur, Paris Cedex, France

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  • Bart-Jan Kullberg,

    Affiliations: Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands, Nijmegen University Center for Infectious Diseases, Nijmegen, The Netherlands

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  • Lionel Le Bourhis,

    Affiliation: Unité de Pathogénie Microbienne Moléculaire, INSERM U389, Institut Pasteur, Paris Cedex, France

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  • Dirk J. de Jong,

    Affiliation: Department of Gastroenterology, Radboud University Medical Center, Nijmegen, The Netherlands

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  • Dennis M. L Langenberg,

    Affiliation: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands

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  • Reinout van Crevel,

    Affiliations: Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands, Nijmegen University Center for Infectious Diseases, Nijmegen, The Netherlands

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  • Gosse J Adema,

    Affiliation: Department of Tumor Immunology, Radboud University Medical Center, Nijmegen, The Netherlands

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  • Tom H. M Ottenhoff,

    Affiliation: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands

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  • Jos W. M. Van der Meer,

    Affiliations: Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands, Nijmegen University Center for Infectious Diseases, Nijmegen, The Netherlands

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  • Mihai G Netea mail

    To whom correspondence should be addressed. E-mail: M.Netea@aig.umcn.nl

    Affiliations: Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands, Nijmegen University Center for Infectious Diseases, Nijmegen, The Netherlands

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  • Published: November 25, 2005
  • DOI: 10.1371/journal.ppat.0010034

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