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Research Article

The OmpA-Like Protein Loa22 Is Essential for Leptospiral Virulence

  • Paula Ristow,

    Affiliations: Unité de Biologie des Spirochètes, Institut Pasteur, Paris, France, Instituto de Microbiologia Professor Paulo de Goes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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  • Pascale Bourhy,

    Affiliation: Unité de Biologie des Spirochètes, Institut Pasteur, Paris, France

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  • Flávia Weykamp da Cruz McBride,

    Affiliation: Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil

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  • Claudio Pereira Figueira,

    Affiliation: Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Brazil

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  • Michel Huerre,

    Affiliation: Unité de Recherche et d'Expertise Histotechnologie et Pathologie, Institut Pasteur, Paris, France

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  • Patrick Ave,

    Affiliation: Unité de Recherche et d'Expertise Histotechnologie et Pathologie, Institut Pasteur, Paris, France

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  • Isabelle Saint Girons,

    Affiliation: Unité de Biologie des Spirochètes, Institut Pasteur, Paris, France

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  • Albert I Ko,

    Affiliations: Instituto de Microbiologia Professor Paulo de Goes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, Division of International Medicine and Infectious Disease, Weill Medical College of Cornell University, New York, New York, United States of America

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  • Mathieu Picardeau mail

    To whom correspondence should be addressed. E-mail: mpicard@pasteur.fr

    Affiliation: Unité de Biologie des Spirochètes, Institut Pasteur, Paris, France

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  • Published: July 13, 2007
  • DOI: 10.1371/journal.ppat.0030097

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