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Research Article

Hemolytic C-Type Lectin CEL-III from Sea Cucumber Expressed in Transgenic Mosquitoes Impairs Malaria Parasite Development

  • Shigeto Yoshida mail,

    To whom correspondence should be addressed. E-mail: shigeto@jichi.ac.jp

    Affiliation: Division of Medical Zoology, Department of Infection and Immunity, Jichi Medical University, Tochigi, Japan

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  • Yohei Shimada,

    Affiliation: Division of Medical Zoology, Department of Infection and Immunity, Jichi Medical University, Tochigi, Japan

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  • Daisuke Kondoh,

    Affiliation: Division of Medical Zoology, Department of Infection and Immunity, Jichi Medical University, Tochigi, Japan

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  • Yoshiaki Kouzuma,

    Affiliation: College of Agriculture, Ibaraki University, Ami-machi, Inashiki-gun, Ibaraki, Japan

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  • Anil K Ghosh,

    Affiliation: Department of Molecular Microbiology and Immunology, Malaria Research Institute, Johns Hopkins School of Public Health, Baltimore, Maryland, United States of America

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  • Marcelo Jacobs-Lorena,

    Affiliation: Department of Molecular Microbiology and Immunology, Malaria Research Institute, Johns Hopkins School of Public Health, Baltimore, Maryland, United States of America

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  • Robert E Sinden

    Affiliation: Infection and Immunity Section, Division of Cell and Molecular Biology, Imperial College London, South Kensington, London, United Kingdom

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  • Published: December 21, 2007
  • DOI: 10.1371/journal.ppat.0030192

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