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Research Article

Multiple Reassortment Events in the Evolutionary History of H1N1 Influenza A Virus Since 1918

  • Martha I. Nelson,

    Affiliation: Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Cécile Viboud,

    Affiliation: Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Lone Simonsen,

    Affiliation: Department of Global Health, School of Public Health and Health Services, The George Washington University, Washington, D.C., United States of America

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  • Ryan T. Bennett,

    Affiliation: Wadsworth Center, New York State Department of Health, Albany, New York, United States of America

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  • Sara B. Griesemer,

    Affiliation: Wadsworth Center, New York State Department of Health, Albany, New York, United States of America

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  • Kirsten St. George,

    Affiliation: Wadsworth Center, New York State Department of Health, Albany, New York, United States of America

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  • Jill Taylor,

    Affiliation: Wadsworth Center, New York State Department of Health, Albany, New York, United States of America

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  • David J. Spiro,

    Affiliation: The J. Craig Venter Institute, Rockville, Maryland, United States of America

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  • Naomi A. Sengamalay,

    Affiliation: Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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  • Elodie Ghedin,

    Affiliation: Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Jeffery K. Taubenberger,

    Affiliation: Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Edward C. Holmes mail

    ech15@psu.edu

    Affiliations: Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Published: February 29, 2008
  • DOI: 10.1371/journal.ppat.1000012

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