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Research Article

Transmission of HIV-1 CTL Escape Variants Provides HLA-Mismatched Recipients with a Survival Advantage

  • Denis R. Chopera,

    Affiliation: Institute of Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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  • Zenda Woodman,

    Affiliation: Institute of Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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  • Koleka Mlisana,

    Affiliation: Centre for the AIDS Programme of Research in South Africa, University of Kwa-Zulu Natal, Durban, South Africa

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  • Mandla Mlotshwa,

    Affiliation: National Institute for Communicable Diseases, Johannesburg, South Africa

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  • Darren P. Martin,

    Affiliation: Institute of Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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  • Cathal Seoighe,

    Affiliation: Institute of Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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  • Florette Treurnicht,

    Affiliation: Institute of Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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  • Debra Assis de Rosa,

    Affiliation: National Institute for Communicable Diseases, Johannesburg, South Africa

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  • Winston Hide,

    Affiliation: South African National Bioinformatics Institute, University of the Western Cape, Cape Town, South Africa

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  • Salim Abdool Karim,

    Affiliation: Centre for the AIDS Programme of Research in South Africa, University of Kwa-Zulu Natal, Durban, South Africa

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  • Clive M. Gray,

    Affiliation: National Institute for Communicable Diseases, Johannesburg, South Africa

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  • Carolyn Williamson mail,

    carolyn.williamson@uct.ac.za

    Affiliation: Institute of Infectious Diseases and Molecular Medicine, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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  • and the CAPRISA 002 Study Team
  • Published: March 21, 2008
  • DOI: 10.1371/journal.ppat.1000033

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