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Research Article

Gain of Function Mutations in CgPDR1 of Candida glabrata Not Only Mediate Antifungal Resistance but Also Enhance Virulence

  • Sélène Ferrari,

    Affiliation: Institute of Microbiology, University of Lausanne and University Hospital Center, Lausanne, Switzerland

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  • Françoise Ischer,

    Affiliation: Institute of Microbiology, University of Lausanne and University Hospital Center, Lausanne, Switzerland

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  • David Calabrese,

    Affiliation: Institute of Microbiology, University of Lausanne and University Hospital Center, Lausanne, Switzerland

    Current address: Selexis SA, Plan-les-Ouates/Geneva, Switzerland

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  • Brunella Posteraro,

    Affiliation: Institute of Microbiology, Università Cattolica del Sacro Cuore, Rome, Italy

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  • Maurizio Sanguinetti,

    Affiliation: Institute of Microbiology, Università Cattolica del Sacro Cuore, Rome, Italy

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  • Giovanni Fadda,

    Affiliation: Institute of Microbiology, Università Cattolica del Sacro Cuore, Rome, Italy

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  • Bettina Rohde,

    Affiliation: GATC Biotech AG, Konstanz, Germany

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  • Christopher Bauser,

    Affiliation: GATC Biotech AG, Konstanz, Germany

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  • Oliver Bader,

    Affiliation: Institut für Medizinische Mikrobiologie, Universitätskliniken Göttingen, Göttingen, Germany

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  • Dominique Sanglard mail

    dominique.sanglard@chuv.ch

    Affiliation: Institute of Microbiology, University of Lausanne and University Hospital Center, Lausanne, Switzerland

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  • Published: January 16, 2009
  • DOI: 10.1371/journal.ppat.1000268

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