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Research Article

A Neutralizing Human Monoclonal Antibody Protects against Lethal Disease in a New Ferret Model of Acute Nipah Virus Infection

  • Katharine N. Bossart mail,

    kbossart@bu.edu (KNB); cbroder@usuhs.mil (CCB)

    Affiliation: CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria, Australia

    Current address: Department of Microbiology and National Emerging Infectious Diseases Laboratories Institute, Boston University School of Medicine, Boston, Massachusetts, United States of America

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  • Zhongyu Zhu,

    Affiliations: Protein Interactions Group, CCRNP, CCR, NCI-Frederick, NIH, Frederick, Maryland, United States of America, BRP, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America

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  • Deborah Middleton,

    Affiliation: CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria, Australia

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  • Jessica Klippel,

    Affiliation: CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria, Australia

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  • Gary Crameri,

    Affiliation: CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria, Australia

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  • John Bingham,

    Affiliation: CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria, Australia

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  • Jennifer A. McEachern,

    Affiliation: CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria, Australia

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  • Diane Green,

    Affiliation: CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria, Australia

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  • Timothy J. Hancock,

    Affiliation: CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria, Australia

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  • Yee-Peng Chan,

    Affiliation: Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America

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  • Andrew C. Hickey,

    Affiliation: Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America

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  • Dimiter S. Dimitrov,

    Affiliation: Protein Interactions Group, CCRNP, CCR, NCI-Frederick, NIH, Frederick, Maryland, United States of America

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  • Lin-Fa Wang,

    Affiliation: CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Victoria, Australia

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  • Christopher C. Broder mail

    kbossart@bu.edu (KNB); cbroder@usuhs.mil (CCB)

    Affiliation: Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America

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  • Published: October 30, 2009
  • DOI: 10.1371/journal.ppat.1000642

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