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Research Article

Continuous Quinacrine Treatment Results in the Formation of Drug-Resistant Prions

  • Sina Ghaemmaghami equal contributor,

    equal contributor Contributed equally to this work with: Sina Ghaemmaghami, Misol Ahn

    Affiliations: Institute for Neurodegenerative Diseases, University of California, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America

    X
  • Misol Ahn equal contributor,

    equal contributor Contributed equally to this work with: Sina Ghaemmaghami, Misol Ahn

    Affiliation: Department of Pathology, University of California, San Francisco, California, United States of America

    X
  • Pierre Lessard,

    Affiliations: Institute for Neurodegenerative Diseases, University of California, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America

    X
  • Kurt Giles,

    Affiliations: Institute for Neurodegenerative Diseases, University of California, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America

    X
  • Giuseppe Legname,

    Affiliations: Institute for Neurodegenerative Diseases, University of California, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America

    Current address: Neurobiology Sector, SISSA, Trieste, Italy

    X
  • Stephen J. DeArmond,

    Affiliations: Institute for Neurodegenerative Diseases, University of California, San Francisco, California, United States of America, Department of Pathology, University of California, San Francisco, California, United States of America

    X
  • Stanley B. Prusiner mail

    stanley@ind.ucsf.edu

    Affiliations: Institute for Neurodegenerative Diseases, University of California, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America

    X
  • Published: November 26, 2009
  • DOI: 10.1371/journal.ppat.1000673

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