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Research Article

A Small-Molecule Inhibitor of T. gondii Motility Induces the Posttranslational Modification of Myosin Light Chain-1 and Inhibits Myosin Motor Activity

  • Aoife T. Heaslip,

    Affiliation: Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont, United States of America

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  • Jacqueline M. Leung,

    Affiliation: Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont, United States of America

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  • Kimberly L. Carey,

    Affiliation: Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont, United States of America

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  • Federica Catti,

    Affiliation: School of Chemistry and Centre for Biomolecular Sciences, University of St Andrews, North Haugh, St Andrews, Fife, Scotland, United Kingdom

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  • David M. Warshaw,

    Affiliation: Department of Molecular Physiology and Biophysics, University of Vermont, Burlington, Vermont, United States of America

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  • Nicholas J. Westwood,

    Affiliation: School of Chemistry and Centre for Biomolecular Sciences, University of St Andrews, North Haugh, St Andrews, Fife, Scotland, United Kingdom

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  • Bryan A. Ballif,

    Affiliation: Department of Biology and Vermont Genetics Network Proteomics Facility, University of Vermont, Burlington, Vermont, United States of America

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  • Gary E. Ward mail

    Gary.Ward@uvm.edu

    Affiliation: Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont, United States of America

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  • Published: January 15, 2010
  • DOI: 10.1371/journal.ppat.1000720

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