Advertisement
Research Article

Mycobacterium tuberculosis Peptides Presented by HLA-E Molecules Are Targets for Human CD8+ T-Cells with Cytotoxic as well as Regulatory Activity

  • Simone A. Joosten equal contributor,

    equal contributor Contributed equally to this work with: Simone A. Joosten, Krista E. van Meijgaarden

    Affiliation: Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

    X
  • Krista E. van Meijgaarden equal contributor,

    equal contributor Contributed equally to this work with: Simone A. Joosten, Krista E. van Meijgaarden

    Affiliation: Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

    X
  • Pascale C. van Weeren,

    Affiliation: Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

    X
  • Fatima Kazi,

    Affiliation: Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

    X
  • Annemieke Geluk,

    Affiliation: Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

    X
  • Nigel D. L. Savage,

    Affiliation: Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

    X
  • Jan W. Drijfhout,

    Affiliation: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands

    X
  • Darren R. Flower,

    Affiliation: The Jenner Institute, University of Oxford, Oxford, United Kingdom

    X
  • Willem A. Hanekom,

    Affiliation: South African Tuberculosis Vaccine Initiative, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa

    X
  • Michèl R. Klein,

    Affiliation: Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

    Current address: National Institute for Public Health and the Environment, Bilthoven, The Netherlands

    X
  • Tom H. M. Ottenhoff mail

    t.h.m.ottenhoff@lumc.nl

    Affiliation: Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

    X
  • Published: February 26, 2010
  • DOI: 10.1371/journal.ppat.1000782

Media Coverage of this Article

Found additional news media or blog coverage for the article? Please let us know.