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Research Article

Neisseria meningitidis Induces Brain Microvascular Endothelial Cell Detachment from the Matrix and Cleavage of Occludin: A Role for MMP-8

  • Alexandra Schubert-Unkmeir mail,

    aunkmeir@hygiene.uni-wuerzburg.de

    Affiliation: Institute of Hygiene and Microbiology, University of Würzburg, Würzburg, Germany

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  • Christian Konrad,

    Affiliation: Institute of Hygiene and Microbiology, University of Würzburg, Würzburg, Germany

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  • Heiko Slanina,

    Affiliation: Institute of Hygiene and Microbiology, University of Würzburg, Würzburg, Germany

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  • Florian Czapek,

    Affiliation: Institute of Hygiene and Microbiology, University of Würzburg, Würzburg, Germany

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  • Sabrina Hebling,

    Affiliation: Institute of Hygiene and Microbiology, University of Würzburg, Würzburg, Germany

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  • Matthias Frosch

    Affiliation: Institute of Hygiene and Microbiology, University of Würzburg, Würzburg, Germany

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  • Published: April 29, 2010
  • DOI: 10.1371/journal.ppat.1000874

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