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Research Article

Prolonged Antigen Presentation Is Required for Optimal CD8+ T Cell Responses against Malaria Liver Stage Parasites

  • Ian A. Cockburn,

    Affiliation: Johns Hopkins Malaria Research Institute and Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • Yun-Chi Chen,

    Affiliation: Johns Hopkins Malaria Research Institute and Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • Michael G. Overstreet,

    Affiliation: Johns Hopkins Malaria Research Institute and Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Baltimore, Maryland, United States of America

    Current address: David H. Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America

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  • Jason R. Lees,

    Affiliation: Department of Surgery, University of Maryland at Baltimore, Baltimore, Maryland, United States of America

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  • Nico van Rooijen,

    Affiliation: Vrije Universiteit, VUMC, Department of Molecular Cell Biology, Faculty of Medicine, Amsterdam, The Netherlands

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  • Donna L. Farber,

    Affiliation: Department of Surgery, University of Maryland at Baltimore, Baltimore, Maryland, United States of America

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  • Fidel Zavala mail

    fzavala@jhsph.edu

    Affiliation: Johns Hopkins Malaria Research Institute and Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • Published: May 06, 2010
  • DOI: 10.1371/journal.ppat.1000877

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