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Research Article

Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCV-Specific CD8+ T Cells Is Linked to Antigen Recognition and T Cell Differentiation

  • Bertram Bengsch equal contributor,

    equal contributor Contributed equally to this work with: Bertram Bengsch, Bianca Seigel

    Affiliations: Department of Medicine II, University of Freiburg, Freiburg, Germany, Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany, Faculty of Biology, University of Freiburg, Freiburg, Germany

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  • Bianca Seigel equal contributor,

    equal contributor Contributed equally to this work with: Bertram Bengsch, Bianca Seigel

    Affiliations: Department of Medicine II, University of Freiburg, Freiburg, Germany, Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany, Faculty of Biology, University of Freiburg, Freiburg, Germany

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  • Marianne Ruhl,

    Affiliation: Department of Virology, University of Essen, Essen, Germany

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  • Jörg Timm,

    Affiliation: Department of Virology, University of Essen, Essen, Germany

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  • Martin Kuntz,

    Affiliation: Department of Medicine II, University of Freiburg, Freiburg, Germany

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  • Hubert E. Blum,

    Affiliation: Department of Medicine II, University of Freiburg, Freiburg, Germany

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  • Hanspeter Pircher,

    Affiliation: Department of Immunology, University of Freiburg, Freiburg, Germany

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  • Robert Thimme mail

    Robert.Thimme@uniklinik-freiburg.de

    Affiliation: Department of Medicine II, University of Freiburg, Freiburg, Germany

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  • Published: June 10, 2010
  • DOI: 10.1371/journal.ppat.1000947

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