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Research Article

Vaccinia Virus–Encoded Ribonucleotide Reductase Subunits Are Differentially Required for Replication and Pathogenesis

  • Don B. Gammon,

    Affiliation: Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada

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  • Branawan Gowrishankar,

    Affiliation: Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada

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  • Sophie Duraffour,

    Affiliation: Laboratory of Virology and Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium

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  • Graciela Andrei,

    Affiliation: Laboratory of Virology and Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium

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  • Chris Upton,

    Affiliation: Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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  • David H. Evans mail

    devans@ualberta.ca

    Affiliation: Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada

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  • Published: July 08, 2010
  • DOI: 10.1371/journal.ppat.1000984

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