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Research Article

Fidelity Variants of RNA Dependent RNA Polymerases Uncover an Indirect, Mutagenic Activity of Amiloride Compounds

  • Laura I. Levi equal contributor,

    equal contributor Contributed equally to this work with: Laura I. Levi, Nina F. Gnädig

    Affiliation: Institut Pasteur, Viral Populations and Pathogenesis Lab and CNRS URA3015, Paris, France

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  • Nina F. Gnädig equal contributor,

    equal contributor Contributed equally to this work with: Laura I. Levi, Nina F. Gnädig

    Affiliation: Institut Pasteur, Viral Populations and Pathogenesis Lab and CNRS URA3015, Paris, France

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  • Stéphanie Beaucourt,

    Affiliation: Institut Pasteur, Viral Populations and Pathogenesis Lab and CNRS URA3015, Paris, France

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  • Malia J. McPherson,

    Affiliation: Institut Pasteur, Viral Populations and Pathogenesis Lab and CNRS URA3015, Paris, France

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  • Bruno Baron,

    Affiliation: Institut Pasteur, Plate Forme de Biophysique des Macromolécules et de leurs Interactions, Paris, France

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  • Jamie J. Arnold,

    Affiliation: Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Marco Vignuzzi mail

    marco.vignuzzi@pasteur.fr

    Affiliation: Institut Pasteur, Viral Populations and Pathogenesis Lab and CNRS URA3015, Paris, France

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  • Published: October 28, 2010
  • DOI: 10.1371/journal.ppat.1001163

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